摘要 目的了解不同甲状腺容积校正方法对武汉市学龄儿童的适用性,探索适宜武汉市学龄儿童的甲状腺容积的校正方法。方法2019年5-8月,在武汉市洪山、汉阳、汉南、江夏、东西湖区,按东、西、南、北、中5个方位划分5个抽样片区,每个片区抽取1所小学,每所小学抽取8~10岁非寄宿学生40人(性别均衡)作为调查对象,采集随机1次尿样、家庭食用盐盐样检测尿碘、盐碘含量,测量儿童身高、体重、甲状腺容积。同时,采用身高容积指数1(HVI1)、体重身高容积指数(WHVI)、体质容积指数(BMIV)、体表面积容积指数(BSAV)和身高容积指数2(HVI2)对甲状腺容积进行校正。结果共调查8~10岁儿童1000人,其中男生499人、女生501人;8、9、10岁儿童各269、321、410人。尿碘中位数为247.50μg/L;盐碘中位数为23.20 mg/kg;身高、体重、甲状腺容积分别为140.00(133.00,146.00)cm、31.00(27.00,37.00)kg、2.56(2.13,3.21)ml。共检出甲状腺肿大儿童30人,甲状腺肿大率为3%(30/1000)。男、女生甲状腺容积分别为2.57(2.16,3.28)、2.56(2.10,3.16)ml,不同性别间比较差异无统计学意义(U=-0.981,P>0.05)。8、9、10岁儿童甲状腺容积分别为2.31(1.98,2.81)、2.68(2.13,3.30)、2.74(2.28,3.35)ml,不同年龄间比较差异有统计学意义(H=47.585,P<0.01)。经Spearman相关分析,8、9、10岁儿童原始甲状腺容积与身高、体重均呈正相关(P均<0.01)。经HVI1校正后,8岁儿童甲状腺容积与身高未见相关性(P>0.05),与体重呈正相关(P<0.01);9、10岁儿童甲状腺容积与身高、体重均呈正相关(P均<0.01)。经WHVI校正后,8、9、10岁儿童甲状腺容积与身高、体重均呈负相关(P均<0.01)。经BMIV校正后,8、9、10岁儿童甲状腺容积与身高均呈正相关(P均<0.01);10岁儿童甲状腺容积与体重呈负相关(P<0.05)。经BSAV校正后,9岁儿童甲状腺容积与体重呈正相关(P<0.05)。经HVI2校正后,9岁儿童甲状腺容积与体重呈正相关(P<0. Objective To understand the applicability of different thyroid volume correction methods for school-age children in Wuhan,and to explore the appropriate thyroid volume correction methods for school-age children in Wuhan.Methods From May to August 2019,Hongshan,Hanyang,Hannan,Jiangxia and Dongxihu districts of Wuhan were divided into five sampling areas according to five directions:east,west,south,north and middle.One primary school was selected from each area,and 40 non-boarding students aged 8-10 years old(gender balanced)were selected from each primary school as survey subjects.Random urine sample and household edible salt sample were collected to detect urinary iodine and salt iodine contents,and the height,weight and thyroid volume of the children were measured.At the same time,the thyroid volume was corrected by height corrected volume index 1(HVI1),weight and height corrected volume index(WHVI),body mass index corrected volume(BMIV),body surface area corrected volume(BSAV)and height corrected volume index 2(HVI2).Results A total of 1000 children aged 8-10 years old were investigated,including 499 boys and 501 girls;among them,there were 269,321 and 410 children aged 8,9 and 10 years old,respectively.The median urinary iodine was 247.50μg/L;the median salt iodine was 23.20 mg/kg;the height,weight and thyroid volume were 140.00(133.00,146.00)cm,31.00(27.00,37.00)kg and 2.56(2.13,3.21)ml,respectively.A total of 30 children with goiter were detected,and the goiter rate was 3%(30/1000).The thyroid volumes of boys and girls were 2.57(2.16,3.28)and 2.56(2.10,3.16)ml,respectively,and the difference was not statistically significant(U=-0.981,P>0.05).The thyroid volumes of children aged 8,9 and 10 years old were 2.31(1.98,2.81),2.68(2.13,3.30)and 2.74(2.28,3.35)ml,respectively,and the differences were statistically significant(H=47.585,P<0.01).Spearman correlation analysis showed that the original thyroid volume was positively correlated with height and weight in children aged 8,9 and 10 years old(P<0.01).After HVI1
出处 《中华地方病学杂志》 CAS 北大核心 2021年第5期404-409,共6页 Chinese Journal of Endemiology
基金 武汉市卫生健康委科研基金(WG20Q02)。
分类号 R73 [医药卫生—肿瘤]
