摘要 目的探讨高龄患者行根治性膀胱切除术的安全性。方法回顾2011年至2015年行根治性膀胱切除术的90例患者资料,根据患者年龄将其分为高龄组及低龄组,比较两组的手术相关情况和围手术期并发症发生情况。结果高龄组与低龄组的手术时间中位数分别为380和435 min,术中出血量中位数分别为1250和1000 ml,术后住院时间中位数均为20 d,输血比例分别为90%和75%,两组间差异均无统计学意义。高龄组与低龄组输血量中位数分别为1200和800 ml,两组间差异有统计学意义。高龄组与低龄组术后短期并发症发生率分别为43.33%和51.67%,术后长期并发症发生率分别为10.00%和13.33%,术后短期轻微并发症发生率分别为36.67%和48.33%,术后短期严重并发症发生率分别为6.67%和3.33%,术后长期轻微并发症发生率分别为6.66%和3.33%,术后长期严重并发症发生率分别为3.33%和10.00%,两组间差异均无统计学意义。结论高龄不是根治性膀胱切除术的禁忌;经过选择的高龄患者,也可以很好的耐受根治性膀胱切除术。 Objective To investigate the safety of radical cystectomy in the elderly patients.Methods We retrospectively analysed the operative data and the post-operative complications on 90 bladder cancer patients who underwent radical cystectomy from 2011 to 2015.According to the age,we divided the patients into the elderly group and their younger counterparts.Results The median operation time of the elderly group and the younger group were 380 min and 435 min,respectively.The median amount of blood loss were 1250 ml and 1000 ml,respectively.The median postoperative hospital stay of both the elder group and the younger group were 20 days.The proportion of blood transfusion were 90%and 75%,respectively.There was no statistically significant difference between the two groups in the above aspects.The median volume of blood transfusion in the elderly group and the younger group were 1200 ml and 800 ml,respectively.There was significant difference between the two groups.The incidence of short-term postoperative complications in the elderly group and the younger group were 43.33%and 51.67%,respectively.The incidence of long-term postoperative complications were 10.00%and 13.33%,respectively.The incidence of short-term mild complications were 36.67%and 48.33%,respectively.The incidence of short-term severe complications were 6.67%and 3.33%,respectively.The incidence of long-term mild complications were 6.66%and 3.33%,respectively.The incidence of long-term severe complications were 3.33%and 10.00%,respectively.The difference between the above two groups was not statistically significant.Conclusions Advanced age is not a contraindication for radical cystectomy.Radical cystectomy seems to be a safe and feasible surgical strategy for the selected elderly bladder cancer patients.
机构地区 四川省肿瘤医院泌尿外科
出处 《现代泌尿生殖肿瘤杂志》 2020年第5期283-287,共5页 Journal of Contemporary Urologic and Reproductive Oncology
分类号 R47 [医药卫生—护理学]
