摘要 目的:观察在常规药物治疗的基础上加用参芪强心汤合温阳利水汤治疗顽固性心衰的临床疗效。方法:将顽固性心衰患者82例随机分为对照组和治疗组各41例。对照组给予常规西药治疗,治疗组在对照组的基础上给予参芪强心汤合温阳利水汤化裁治疗,均持续治疗3个月。观察治疗前后2组中医症状评分以及左室射血分数(LVEF)、左室舒张末期内径(LVEDD)及左室收缩末期内径(LVESD)水平变化;观察2组临床疗效和不良反应。结果:治疗组总有效率为95.12%,高于对照组的60.98%,差异有统计学意义(P<0.05)。治疗后,2组主症、次症和总症状评分均较治疗前下降(P<0.05),且治疗组各项评分均低于对照组(P<0.05)。治疗后,2组LVEF水平均较治疗前升高(P<0.05),LVEDD、LVESD水平均较治疗前降低(P<0.05);且治疗组上述各项指标改善较对照组更显著(P<0.05)。治疗组不良反应发生率为21.95%,对照组为12.20%,2组比较,差异无统计学意义(P>0.05)。结论:参芪强心汤合温阳利水汤治疗顽固性心衰,能有效减轻患者心衰症状,改善患者心功能,提高临床疗效,且安全性良好。 Objective:To observe the clinical effect of Shenqi Qiangxin tang combined with Wenyang Lishui tang on the treatment of refractory heart failure based on the treatment of conventional medicine. Methods:A total of 82 patients with refractory heart failure were randomly divided into the control group and the treatment group,41 cases in each group. The control group was given conventional western medicine for treatment, and the treatment group was additionally given modified Shenqi Qiangxin tang and Wenyang Lishui tang based on the treatment of the control group. Both groups were treated for three months. Before and after treatment,changes in Chinese medicine symptom scores and the heart function indexes including left ventricular ejection fraction(LVEF),left ventricular end-diastolic diameter(LVEDD) and left ventricular end-systolic diameter(LVESD), and the clinical effect as well as adverse reactions were observed in the two groups.Results:The total effective rate was 95.12% in the treatment group,higher than that of 60.98% in the control group,the difference being significant(P<0.05). After treatment, the scores of primary, secondary and total symptoms in the two groups were decreased when compared with those before treatment(P<0.05),and the above scores in the treatment group were lower than those in the control group(P<0.05). After treatment, the LVEF level in both groups was respectively increased when compared with that before treatment(P<0.05),and the levels of LVEDD and LVESD in both groups were decreased when compared with those before treatment(P<0.05);the above levels in the treatment group were improved more significantly than those in the control group(P<0.05). The incidence of adverse reactions was 21.95% in the treatment group and 12.20% in the control group,there being no significant difference(P>0.05). Conclusion:The therapy of Shenqi Qiangxin tang combined with Wenyang Lishui tang for patients with refractory heart failure, can effectively reduce their symptoms,improve the heart function and clinic
机构地区 濮阳市中医院心内科
出处 《新中医》 CAS 2021年第6期38-41,共4页 Journal of New Chinese Medicine
关键词 顽固性心力衰竭 参芪强心汤 温阳利水汤 心功能 Refractory heart failure Shenqi Qiangxin tang Wenyang Lishui tang Heart function
