摘要 肝癌起病隐匿、发展迅速、恶性程度高,临床上发现时多属中晚期,失去了手术治疗的机会。目前,针对中晚期肝癌的转化治疗使不可切除肝癌变成可切除,已成为肝癌治疗的重要策略与新焦点。转化治疗中涉及对病人肝脏功能评估、血清学肿瘤标记物测定、影像学检查分析、术前肝脏体积计算等,同时须根据实体瘤疗效评估标准对不同状况的病人实施个体化转化治疗策略。因此,了解转化治疗中相关指标及其参考价值是肝胆外科医生必备的知识与技能。 Hepatocellular carcinoma(HCC) has insidious onset,rapid development and high degree of malignancy.Clinically,it is often found in the intermediate or advanced stage,and the chance of surgical treatment is lost.At present,conversion therapy for patients with intermediate or advanced stage makes unresectable HCC become resectable,which has become an important strategy and a new focus.Conversion therapy involves liver function assessment, serum tumor markers measurement, imaging examination analysis,preoperative liver volume calculation,etc.Meanwhile,individualized conversion therapy strategies should be implemented for patients with different conditions according to the response evaluation criteria in solid tumors.Therefore, it is an essential skill for hepatobiliary surgeons to understand the relevant indexes and their reference value in conversion therapy.
出处 《中国实用外科杂志》 CAS CSCD 北大核心 2021年第3期337-342,共6页 Chinese Journal of Practical Surgery
基金 辽宁省自然科学基金(No.2017225032) 沈阳市科学技术计划(No.17-230-9-16)。
分类号 R6 [医药卫生—外科学]
