摘要 胆囊癌恶性程度高,易侵犯邻近脏器和发生淋巴结转移,且对放化疗不敏感,是预后最差的胆道恶性肿瘤。根治性手术切除仍然是目前唯一有可能治愈胆囊癌的手段,但是关于胆囊癌的手术方式、肝脏切除范围、淋巴结清扫范围、意外胆囊癌的处理等方面仍存在诸多争议。此外,当前免疫治疗和靶向治疗在多种实体瘤中取得巨大成功的背景下,未来外科手术在进展期胆囊癌治疗中的地位是否会发生改变,亦值得我们进一步思考。 Gallbladder cancer is a high malignancy which is predisposed to invade adjacent organs and have lymph node metastasis.Gallbladder cancer is not sensitive to radiotherapy or chemotherapy with the worst prognosis among biliary tract cancers.At present,radical resection is the only possible method to cure gallbladder cancer.However,there are still many controversies about the surgical strategies,the extent of liver resection and lymph node dissection,and the treatment of incidental gallbladder cancer.In addition,under the background of the great success of immunotherapy and targeted therapy in a variety of solid tumors,it is also a question worthy of further considerations that whether the status of surgery in the treatment of advanced gallbladder cancer will be changed in the near future.
出处 《肿瘤防治研究》 CAS CSCD 2021年第4期321-326,共6页 Cancer Research on Prevention and Treatment
基金 国家自然科学基金(81972256) 上海市医学重点专科建设项目——普外科(ZK2019B18) 上海市普陀区临床特色专病建设项目(2020tszb03)。
关键词 胆囊癌 外科治疗 腹腔镜手术 意外胆囊癌 Gallbladder cancer Surgical treatment Laparoscopic surgery Incidental gallbladder cancer
分类号 R735.8 [医药卫生—肿瘤]
