摘要 目的通过胎儿肺静脉(PV)及二尖瓣口血流频谱评价孕晚期孤立性单脐动脉心脏舒张功能。方法应用彩色多普勒检测孕28~39周孤立性单脐动脉(ISUA)胎儿34例及与其孕龄匹配正常组胎儿肺频谱及二尖瓣口频谱,测量PV流速及速度比,流速包括心室收缩期峰值流速S、心室收缩末期流速v、心室舒张早期流速D、心房收缩期峰值流速a,速度比包括静脉搏动指数PIV、S/v、S/D、S/a、v/D、v/a及D/a;测量二尖瓣口E峰及A峰流速并计算E/A比值;并随访两组产后新生儿出生后体质量及胎盘情况。结果两组PIV、S/v、S/D、S/a、v/D、v/a、D/a及二尖瓣口E/A比值均无明显变化(P>0.05);ISUA组及正常组各速度比与三尖瓣口E/A比值进行相关性分析,两组中PIV与E/A比值相关性较好(ISUA组R2为0.646,正常组R2为0.579);ISUA组新生儿体质量及胎盘质量与正常组比较,差异均有统计学意义(P<0.05)。结论 ISUA组及正常组中PIV与二尖瓣E/A比值相关性更好,通过PIV可能更早期识别ISUA胎儿左心舒张功能变化。 Objective By detecting fetal pulmonary venous(PV) blood flow parameter of isolated single umbilical artery(ISUA) in third trimester, to reflect the function of fetal left ventricular diastolic. Methods Color Doppler was employed to visualize the spectra of the fetal PV and mitral orifice in 34 fetuses with ISUA aged 28-39 weeks and in age-matched healthy controls. The PV flow velocities and velocity ratios were measured. The flow velocities included the ventricular systolic peak flow velocity "S" late diastolic flow velocity "v" early diastolic flow velocity "D" and atrial systolic flow velocity "a". The velocity ratios included PIV, S/v, S/D, S/a, v/D, v/a, and D/a. The E peak and A peak flow velocities at the mitral orifice were measured, and the E/A ratio was calculated. The birth weight and placental quality between the ISUA and control groups in the third trimester groups were analyzed based on the postpartum results. Results There were no significant differences in the ratios of PIV, S/v, S/D, S/a, v/D, v/a, D/a and mitral valve E/A in the two groups(P>0.05). Correlation analysis was performed between the speed ratio of the normal group and the mitral valve E/A ratio. The correlation between PIV and E/A ratio was better in the two groups(R2 of 0.646 in the isolated SUA group and 0.579 in the control group). The birth weight and the quality of the placenta between ISUA and normal group were statistically significant(P<0.05). Conclusions The PIV and mitral E/A ratios are better in the ISUA group and the normal group. The left ventricular diastolic function of the ISUA fetus may be identified earlier by PIV.
机构地区 兰州大学第二医院超声科 甘肃省妇幼保健院超声科
出处 《中国超声医学杂志》 CSCD 北大核心 2021年第4期411-414,共4页 Chinese Journal of Ultrasound in Medicine
关键词 肺静脉 孤立性单脐动脉 二尖瓣 胎儿 心脏 舒张功能 Pulmonary venous Isolated single umbilical artery Mitral valve Fetus Cardiac Diastolic function
分类号 R54 [医药卫生—心血管疾病]
