摘要 目的:分析病人健康问卷(PHQ-9)和广泛性焦虑量表(GAD-7)在非心源性胸痛(non-cardiac chest pain, NCCP)患者中应用的效度和信度,探索快速筛查焦虑抑郁的可行性。方法:连续选取2017-2018年就诊的非心源性胸痛患者343人。完成PHQ-9和GAD-7评定,随机抽取30人重测。采用Cronbach α系数评估内部一致性,以精神科医生应用简明国际神经精神访谈(MINI),根据ICD-10做出的诊断为"金标准"评估效标效度,采用受试者工作特征曲线(ROC)检验诊断效能。结果:PHQ-9 Cronbach’α系数为0.89,重测信度为0.85,最佳分界值11分,灵敏度81%,特异度84%,ROC曲线下面积(AUC)为0.90。GAD-7 Cronbach α系数为0.92,重测信度为0.83。最佳分界值8分,灵敏度为96%,特异度为38%,ROC的AUC为0.61。结论:NCCP患者抑郁评估中PHQ-9具有良好的效度和信度,焦虑评估中GAD-7特异度不理想。 Objective:To assess the validity and reliability of the Patients’ Health Questionnaire Depression Scale-9 item(PHQ-9) and Generalized Anxiety Disorder 7-item scale(GAD-7)in patients with non-cardiac chest pain(NCCP),and to explore the feasibility of rapid screening of anxiety and depression.Methods:Totally 343 patients with NCCP from 2017 to 2018 were selected and assessed with the PHQ-9 and GAD-7.Thirty patients wererandomly selected to be retested.Cronbach α coefficient was used to evaluate the internal consistency.The criterion validity was evaluated with the gold standard of the diagnosis made by psychiatrists with the Mini International Neuropsychological Interview(MINI) according to ICD-10.Receiver operating characteristic(ROC) curve was used to test the diagnosis efficiency.Results:The Cronbach α coefficient of PHQ-9 was 0.89,the retest reliability was 0.85,the best boundary value was 11 points, the sensitivity was 81%,the specificity was 84%,and the area under ROC curve(AUC) was 0.90.The Cronbach α coefficient of GAD-7 was 0.92,the retest reliability was 0.83,the bestboundary value was 8 points, the sensitivity was 96%,the specificity was 38%,and the AUC was 0.61.Conclusion:The PHQ-9 has good validity and reliability in patients with NCCP,while the validity of GAD-7 is not ideal.
机构地区 北京大学人民医院精神科 北京大学人民医院心内科
出处 《中国心理卫生杂志》 CSCD 北大核心 2021年第5期376-381,共6页 Chinese Mental Health Journal
基金 远程监控下居家运动康复对稳定性冠心病患者的影响(20180119)。
关键词 非心源性胸痛 抑郁 效度 信度 病人健康问卷 广泛性焦虑量表 non-cardiac chest pain depression validity reliability PHQ-9 GAD-7
