摘要 目的:系统评价产妇贫血与产后抑郁的关系。方法:检索PubMed、Web of Science、Embase、Cochrane Library、CINAHL Plus、PsycINFO、中国生物医学文献数据库、中国知网、万方、维普数据库中探讨产妇贫血与产后抑郁关系的研究,检索时限均为建库至2020年2月20日,并对纳入的文献进行质量评价与数据提取,采用RevMan 5.3与Stata 14.0软件进行meta分析。结果:最终纳入8篇文献,共78 637例患者。纳入文献质量评价均在中等及以上。meta分析显示产妇贫血与产后抑郁呈正关联(OR=2.08,95%CI:1.55~2.80,P<0.001);同时,亚组分析显示,不同地区[欧洲(OR=2.91)、亚洲(OR=1.82)]、抑郁评估期[产后6周及以下(OR=1.93)、产后6周以上(OR=2.48)]、贫血评估期[产后6周及以下(OR=2.17)、产后6周以上(OR=2.02)]、产妇贫血界定标准[Hb (OR=1.93)、其他(OR=2.48)]、产妇抑郁症状测量工具[EPDS (OR=2.01)、其他(OR=2.64)]中产妇贫血均与产后抑郁呈正关联。结论:产妇贫血与产后抑郁的风险增加有关。 Objective:To systematically evaluate the relationship between maternal anemia and postpartum depression.Methods:A search was conducted in PubMed, Web of Science, Embase, Cochrane Library, CINAHL Plus, PsycINFO,CBM,CNKI,Wanfang, and VIP to explore the relationship between anemia and postpartum depression in women.The database were searched from inception to February 20,2020 and the included literatures will be evaluated for quality and data extraction.meta analysis will be performed using RevMan 5.3 and Stata 14.0 software.Results:A total of 8 literatures with a total of 78 637 patients were included in the study.The quality of included literatures were all moderate and above.meta analysis showed that maternal anemia was positively associated with postpartum depression(OR=2.08,95% CI:1.55-2.80,P<0.001).At the same time, subgroup analysis showed that anemia was positively associated with postpartum depression under the different regions [Europe(OR=2.91),Asia(OR=1.82)],depression assessment period [postpartum 6 weeks and less(OR=1.93),postpartum more than 6 weeks(OR=2.48)],anemia assessment period [postpartum 6 weeks and less(OR=2.17),postpartum more than 6 weeks(OR=2.02)],maternal anemia definition criteria [Hb(OR=1.93),others(OR=2.48)],maternal depression symptom measurement tool [EPDS(OR=2.01) and others(OR=2.64)].Conclusion:Maternal anemia is associated with an increased risk of postpartum depression.
机构地区 河南大学商学院 河南大学护理与健康研究所
出处 《中国心理卫生杂志》 CSCD 北大核心 2021年第5期382-388,共7页 Chinese Mental Health Journal
基金 河南大学研究生教育创新与质量提升计划项目(SYL18060142)。
